Panama Canal Cruises

Compare 14 Panama Canal cruises in our guide, sailing with 7 cruise lines on itineraries from 7 Nights to 22 Nights. Every cruise includes the full port-by-port itinerary, an interactive route map, and traveler insights sourced from real reviews.

The first thing to check is whether the cruise goes through the canal or only into it. A full transit is an ocean-to-ocean voyage: the crossing itself takes roughly eight to ten hours through three sets of locks, Gatun Lake and the Culebra Cut, and the cruise around it is a long one-way trip - Florida to Los Angeles, or even Seattle, typically two weeks or more. A partial transit is a round trip from Fort Lauderdale or Miami that rises through the Gatun Locks into Gatun Lake, spends the day there while some passengers go ashore on excursions, and turns back. It shows you the locks without the cross-country commitment.

Canal day is the whole point, so it is worth planning. Most ships make the crossing during daylight and it fills the day, so don't plan on much else. Move around rather than staking out one spot - forward and aft, high and low decks each show the locks differently - and watch for the films or lectures most ships run beforehand to explain what you are about to see.

Cruise season runs roughly from autumn to spring, with most full transits scheduled as ships reposition between Alaska or the West Coast and the Caribbean. December through early March is the drier stretch and the most expensive; October and November are wetter and cheaper, and the rains return from around mid-March.

Because a full transit starts and ends on different coasts, you need a passport and two one-way flights. These trips suit retirees and anyone with two weeks or more to spare who likes engineering and sea days; travelers tied to school holidays usually take the partial transit instead.

Sources: voyagerinfo.com, thepointsguy.com, directlinecruises.com

Port guides for Panama Canal

Panama Canal itineraries

Celebrity Ascent cruise ship
$
Panama Canal
11 Nights · 6 Ports
Celebrity Cruises·Celebrity Ascent

Celebrity Ascent - Panama Canal & Southern Caribbean

4.6(160 reviews)

Departs Fort Lauderdale, FL

CartagenaPanama Canal (Transit)Panama Canal (Transit)Oranjestad+2 more
Bucket List TravelersCouples
Rotterdam cruise ship
$
Panama Canal
12 Nights · 6 Ports
Holland America Line·Rotterdam

Rotterdam - Panama Canal Sunfarer from Fort Lauderdale

4.4(336 reviews)

Departs Fort Lauderdale, FL

Half Moon CayWillemstadCartagenaPanama Canal (Transit)+2 more
Classic CruisersRetirees
Norwegian Encore cruise ship
$
Panama Canal
22 Nights · 12 Ports
Norwegian Cruise Line·Norwegian Encore

Norwegian Encore - Panama Canal Repositioning

4.3(831 reviews)

Departs Miami, FL

CartagenaPanama Canal (Transit)Panama City (Fuerte Amador)Puntarenas+8 more
SeniorsAdventure Seekers
Norwegian Bliss cruise ship
$
Panama Canal
16 Nights · 8 Ports
Norwegian Cruise Line·Norwegian Bliss

Norwegian Bliss - Panama Canal from Los Angeles to Miami

4.2(1,555 reviews)

Departs Los Angeles, CA

Cabo San LucasAcapulcoPuerto QuetzalPuerto Caldera+4 more
SeniorsHistory Buffs
Norwegian Joy cruise ship
$
Panama Canal
21 Nights · 11 Ports
Norwegian Cruise Line·Norwegian Joy

Norwegian Joy - Panama Canal Repositioning: Seattle to Miami

4.2(1,124 reviews)

Departs Seattle, WA

Victoria, BCSan Francisco, CASan Francisco, CALos Angeles, CA+7 more
Bucket List TravelersScenic Cruisers
Nieuw Amsterdam cruise ship
$
Panama Canal
12 Nights · 6 Ports
Holland America Line·Nieuw Amsterdam

Nieuw Amsterdam - Panama Canal Discovery: Costa Rica & Greater Antilles

4.2(839 reviews)

Departs Fort Lauderdale, FL

Half Moon CayOranjestadCartagenaPanama Canal (Transit)+2 more
SeniorsCouples
Marina cruise ship
$$$
Panama Canal
20 Nights · 15 Ports
Adults Only
Oceania Cruises·Marina

Marina - Panama Canal Navigator: Double Transit from Miami

4.2(242 reviews)

Departs Miami, FL

CozumelCosta MayaHarvest CayeSanto Tomas de Castilla+11 more
FoodiesLuxury Travelers
Eurodam cruise ship
$
Panama Canal
21 Nights · 11 Ports
Holland America Line·Eurodam

Eurodam - Panama Canal Repositioning: Seattle to Fort Lauderdale

4.1(1,170 reviews)

Departs Seattle, WA

Vancouver, BCSanta Barbara, CASan Diego, CACabo San Lucas+7 more
Bucket List TravelersScenic Cruisers
Emerald Princess cruise ship
$
Panama Canal
16 Nights · 7 Ports
Princess Cruises·Emerald Princess

Emerald Princess - Panama Canal Ocean to Ocean

4(1,249 reviews)

Departs Los Angeles, CA

Puerto VallartaHuatulcoPuerto QuetzalPuntarenas+3 more
SeniorsHistory Buffs
Zuiderdam cruise ship
$$
Panama Canal
14 Nights · 5 Ports
Holland America Line·Zuiderdam

Zuiderdam - Panama Canal Passage

4(811 reviews)

Departs Fort Lauderdale, FL

Half Moon CayOranjestadCartagenaPanama Canal (Transit)+1 more
Bucket List SeekersHistory Buffs
Queen Elizabeth cruise ship
$
Panama Canal
20 Nights · 7 Ports

Queen Elizabeth - Panama Canal Crossing: Miami to Seattle

4(159 reviews)

Departs Miami, FL

CartagenaPanama Canal (Transit)Panama Canal (Transit)Puntarenas+3 more
Classic CruisersBucket List Travelers
Caribbean Princess cruise ship
$
Panama Canal
12 Nights · 5 Ports
Princess Cruises·Caribbean Princess

Caribbean Princess - Panama Canal from Fort Lauderdale

3.9(2,001 reviews)

Departs Fort Lauderdale, FL

WillemstadCartagenaPanama Canal (Transit)Puerto Limon+1 more
SeniorsHistory Buffs
Norwegian Jade cruise ship
$
Panama Canal
11 Nights · 8 Ports
Norwegian Cruise Line·Norwegian Jade

Norwegian Jade - Panama Canal Repositioning: Tampa to Panama City

3.9(1,528 reviews)

Departs Tampa, FL

Key West, FLCozumelGeorge TownOcho Rios+4 more
Value SeekersBucket List Travelers
Wind Star cruise ship
$$$$
Panama Canal
7 Nights · 5 Ports
Windstar Cruises·Wind Star

Wind Star - Costa Rica & Panama Canal

Departs Panama Canal (Transit)

Panama City (Fuerte Amador)Panama City (Fuerte Amador)Isla ParidaGolfo Dulce (Puerto Jimenez)+1 more
Nature LoversCouples